Short CV for Professor Udit:

 

 

Education                                                                                                                                                           

 

CIHR Fellow and Research Associate in Chemical Biology, under M.G. Finn

Jun 2006 to Aug 2008, The Scripps Research Institute, La Jolla, CA, U.S.A.

 

HHMI Teaching and Research Fellow, Occidental College, under M.G. Hill

Jun 2005 to Jun 2006, Occidental College, Los Angeles, CA, U.S.A.

 

Ph.D., Chemistry, under F.H. Arnold and H.B. Gray

Jun 2005, California Institute of Technology, Pasadena, CA, U.S.A.

 

Honours B.Sc., Chemistry and Biochemistry, under P.M. Macdonald; Minor, Physics; Cumulative GPA 3.93 (High Distinction)

May 2000, University of Toronto, Toronto, Ontario, Canada

 

 

 

Selected Awards and Honours                                                                                                          

 

·     Member of the American Chemical Society.

·     Camille and Henry Dreyfus Foundation Faculty Start-up Award.  Occidental College – Aug 2008

·     Canadian Institutes of Health Research Fellow.  The Scripps Research Institute – July 2007 to Aug 2008

·     Society of Fellows Award for Research.  The Scripps Research Institute – Oct 2007

·     Howard Hughes Medical Institute Fellow.  Occidental College – Jun 2005 to Jun 2006

·     Natural Sciences and Engineering Research Council of Canada (NSERC) Post Graduate Scholarship.  California Institute of Technology – May 2001 to Jun 2005

·     Willits Foundation Scholarship.  California Institute of Technology – Sept 2000 to Jun 2001

·     Peter Hein Award in Physics.  University of Toronto – Mar 2000

·     E.A. Robinson Medal.  University of Toronto – Jun 2000

·     Willits Foundation Scholarship.  University of Toronto – Sept 1999 to May 2000

 

 

 

Publications

 

1.      A.K. Udit, C. Everett, A.J. Gale, J. Reiber-Kyle, M. Ozkan, M.G. Finn.  Polyvalent Display of Cationic Motifs on Bacteriophage Q with anti-Heparin Activity.  ChemBioChem, submitted July 2008.

2.      A.K. Udit, S. Brown, M.M. Baksh, M.G. Finn.  Polyvalent Display of Metal-bindng Hexahistidine Motifs on Bacteriophage Q.  J. Inorg. Biochem., in press (2008).

3.      V. Hong, A.K. Udit, M.G. Finn.  Electrochemically Protected Copper(I)-Catalyzed Azide-Alkyne Cycloaddition.  ChemBioChem, (2008) 9:1481-1486.

4.      D.E. Prasuhn Jr., J. Kuzelka, A.K. Udit, E. Strable, G.C. Lander, J.D. Quispe, A. Zlotnick, C. Potter, B. Carragher, M.G. Finn.  Polyvalent Display of Iron Protoporphyrin IX on Hepatitis B Virus Capsid Protein through Coordination to Hexa(Histidine) Tags.  Chemistry and Biology, (2008) 15(5):513-519.

5.      E. Strable, D.E. Prasuhn Jr., A.K. Udit, S.D. Brown, A.J. Link, J.T. Ngo, G. Lander, J. Quispe, C.S. Potter, B. Carragher, D.A. Tirrell, M.G. Finn.  Unnatural Amino Acid Incorporation into Virus-like Particles.  Bioconjugate Chem. (2008) 19:866-875.  Featured on the cover.

6.      A.K. Udit, S.M. Contakes, H.B. Gray.  “P450 Electron Transfer Reactions” in Metal Ions in Life Sciences; A. Sigel, H. Sigel, R.K.O. Sigel, Eds.; John Wiley & Sons (2007) Vol. 3, pp. 157-185.

7.      D.M. Ceres, A.K. Udit, H.D. Hill, M.G. Hill, J.K. Barton.  Differential Ionic Permeation of DNA-Modified Electrodes.  J. Phys. Chem. B (2007) 111:663-668.

8.      A.K. Udit, M.G. Hill, H.B. Gray.  Electrochemistry of Cytochrome P450 BM3 in Sodium Dodecyl Sulfate Films.  Langmuir (2006) 22: 10854-10857.

9.      A.K. Udit, K.D. Hagen, P.J. Goldman, A. Star, J.M. Gillan, H.B. Gray, M.G. Hill.  Electrochemical and Spectroscopic Investigations of Cytochrome P450 BM3-Surfactant Film Assemblies.  J. Am. Chem. Soc. (2006) 128: 10320-10325.

10.  A.K. Udit, M.G. Hill, H.B. Gray.  Electrochemical Generation of a High-valent state of Cytochrome P450. J. Inorg. Biochem. (2006) 100: 519-523.

11.  A.K. Udit, H.B. Gray.  Electrochemistry of Heme-Thiolate Proteins.  Biochem. Biophys. Res. Commun. (2005) 338: 470-476.

12.  A.K. Udit, W. Belliston-Bittner, E.C. Glazer, Y.H.L. Nguyen, J.M. Gillan, M.G. Hill, M.A. Marletta, D.B. Goodin, H.B. Gray.  Redox Couples of Inducible Nitric Oxide Synthase.  J. Am. Chem. Soc. (2005) 127: 11212-11213.

13.  A.K. Udit, N. Hindoyan, M.G. Hill, F.H. Arnold, H.B. Gray.  Protein-Surfactant Film Voltammetry of Wild Type and Mutant Cytochrome P450 BM3.  Inorg. Chem. (2005) 44: 4109-4111.

14.  A.K. Udit, M.G. Hill, V.G. Bittner, F.H. Arnold, H.B. Gray.  Reduction of dioxygen catalyzed by pyrene-wired heme domain cytochrome P450 BM3 electrodes.  J. Am. Chem. Soc. (2004) 126: 10218-1021.

15.  A.K. Udit, F.H. Arnold, H.B. Gray.  Cobaltocene-mediated catalytic monooxygenation using holo and heme domain cytochrome P450 BM3.  J. Inorg. Biochem. (2004) 98: 1547-1550.

16.  N. Mackinnon, K.J. Crowell, A.K. Udit, P.M. Macdonald.  Aluminum Binding to Phosphatidylcholine Lipid Bilayer Membranes: 27Al and 31P NMR Spectroscopic Studies.  Chem. Phys. Lipids. (2004) 132: 23-36.

17.  A.K. Udit, J.J. Silberg, V. Sieber.  “Sequence Homology-Independent Protein Recombination (SHIPREC)” in Methods in Molecular Biology: Directed Evolution Library Creation; F.H. Arnold, G. Georgiou, Eds.; Humana Press (2003) Vol. 231, pp 153-163.

 

 

 

Primary Techniques Utilized in the Laboratory                                                                                                                                      

 

solid-phase peptide synthesis; basic carbohydrate synthesis; MALDI-MS analysis of peptides/proteins; electrochemistry; inorganic synthesis; general molecular biology (PCR, cloning, protein expression from E. coli, etc.); protein biochemistry and purification (e.g., FPLC); GC-MS analysis; UV-Vis and IR spectroscopy; NMR

 

 

 

Other Selected Experiences

 

Columnist and Exhibits Presenter / Interpreter, Birch Aquarium at Scripps Institution of Oceanography

Jun 2006 to Aug 2008; La Jolla, CA, U.S.A.

·     Contributed science-related articles to the aquarium’s monthly newsletter, The High Tide Times

·     Educated visitors about marine life and conservation through hands-on demonstrations and field trips

 

Mentor, Summer Undergraduate Research Fellowship Program, California Institute of Technology

Summer 2003; Pasadena, CA, U.S.A.

·     Developed and supervised a research project for an undergraduate student involving synthetic chemistry, electrochemistry, and protein biophysics

 

Safety Officer, Arnold Research Group, California Institute of Technology

Sept 2002 to Aug 2004; Pasadena, CA, U.S.A.

·     Maintained a safe working environment: proper waste disposal, chemical storage, maintained emergency and First Aid kits, trained new lab members in safety practices

 

Senior Teaching Assistant, Chemistry Department, California Institute of Technology

Aug 2000 to Dec 2003; Pasadena, CA, U.S.A.

·     Organized and instructed two laboratory classes: Introduction to Chemistry and Analytical Chemistry

 

President, Erindale Chemistry and Physics Society, University of Toronto

May 1999 to May 2000; Toronto, ON, CAN

·     Managed the Executive Committee.  Provided tutorials and social events for students, organized field trips to research institutes, and invited guest lecturers.